Diazepam is highly lipid-soluble which is widely distributed throughout the physique after administration. It easily crosses the two the blood–brain barrier as well as placenta, and is also excreted into breast milk.

Withdrawal signs or symptoms can take place from conventional dosages and in addition right after brief-term use, and might range from insomnia and anxiousness to extra critical signs, like seizures and psychosis.

El diazepam puede ocasionar efectos secundarios. Informe a su médico si cualquiera de estos síntomas se vuelve severo o no desaparece:

地西泮在口服後，迅速被身體吸收，藥效很快開始，以靜脈注射，藥效更快。地西泮經肝臟代謝，其代謝物經腎臟排泄，只有極少量的地西泮沒有被代謝便排泄。

cyclophosphamide will increase the amount or impact of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Not known.

Any other medicine that causes dizziness and sleepiness, which include prescription soreness medicines, slumber medicines, and medicines for anxiousness

Diazepam, just like other benzodiazepine prescription drugs, can cause tolerance, Actual physical dependence, compound use condition, and benzodiazepine withdrawal syndrome. Withdrawal from diazepam or other benzodiazepines frequently leads to withdrawal signs just like Individuals noticed all through barbiturate or Liquor withdrawal.

fluconazole will boost the stage or influence of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.

polices and scheduling than other benzodiazepines.48a Even though one actions from diazepam have

acetazolamide will increase the amount or impact of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unfamiliar.

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Diazepam can influence your alertness or coordination. Never generate or do other pursuits that require alertness or coordination right up until you know the way diazepam has an effect on you.

A get more info call to prescribe diazepam rectal gel includes more than the analysis and choice of right dose

buprenorphine subdermal implant and diazepam both of those boost sedation. Avoid or Use Alternate Drug. Restrict use to patients for whom choice treatment method possibilities are insufficient